Фенотипические маркеры синдрома недифференцированной дисплазии соединительной ткани у детей с приобретенной близорукостью

Abstract

Цель. Оценить фенотипические маркеры недифференцированной дисплазии соединительной ткани у детей с приобретенной близорукостью. Phenotypic markers of undifferentiated connective-tissue dysplasia in children with myopia were revealed in 55.2±3.3% of cases. The main factors of risk of myopia progression in children aged 7-11 years are the expressed venous network on the skin (OR = 7.8; 95% CI = 2.9 -20.7, p <0.05), the asthenic body type (OR = 4.9; 95% CI = 2.1-11.8, p<0.05), platypodia (OR = 4.0; 95% CI = 1.7-9.5, p <0.05), malocclusion, abnormal teeth, multiple caries (OR = 3.2; 95% CI = 1.3-7.8, p <0.05). In children of 12-15 years main risk factors of progression of myopia are moderate or severe connective tissue dysplasia (OR = 7.9; 95% CI = 3.2-19.3, p <0.05), the asthenic body type (OR = 7.1; 95% CI = 3.2-15.7), valve prolapses and other small cardiac anomalies (OR = 6.9; 95% CI = 3.1-15.3, p <0.05), joint hypermobility (OR = 6.1; 95% CI = 2,7- 13.6, p <0.05), a violation of posture, scoliosis (OR = 5.6; 95% CI = 2,5-12,4, p <0.05) and increased skin elasticity (OR = 5.3; 95% CI = 2.3-12.5, p <0.05).