Дослідження рівня 25-гідроксивітаміну Д, ретинолу та токоферолу у дітей з прогресуючою міопією

Abstract

Мета. Дослідити рівні 25-гідроксивітаміну Д, ретинолу та токоферолу у ротовій рідині дітей з прогресуючою міопією. Objective: To investigate the levels of 25-hydroxyvitamin D, retinol, and tocopherol in the oral fluid of children with progressive myopia. 34 children (68 eyes) with mild myopia were examined. Group I - 16 children (32 eyes) - with progressive myopia and Group II - 18 children (36 eyes) - with stable myopia. The control group - 18 relatively healthy children (36 eyes). In children with progressive myopia, vitamin levels were reduced: the level of 25-hydroxyvitamin D was 1.2 times lower than in children in group II and 2.4 times lower than in children in the control group, retinol was 1.2 times lower than in children in group II and 2.3 times lower than in children in the control group, 1.3 times lower than in group II, 3 times lower than in conditionally healthy children. (p<0.05). According to ROC analysis, it was found that the optimal values for the progressive course of myopia in oral fluid are the following: ≤ 20.154 ng/ml for 25-hydroxyvitamin D, ≤ 99.602 ng/ml for retinol level and ≤ 5.129 μg/ml for tocopherol level (p<0.05).