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Please use this identifier to cite or link to this item: http://dspace.zsmu.edu.ua/handle/123456789/11233

Название: Study of antioxidant properties of 7-benzyl-8-benzylidene hydrazine xanthine derivatives in vitro and in vivo
Авторы: Yevseyeva, L.
Romanenko, M.
Aleksandrova, K.
Ivanchenko, D.
Levich, S. V.
Pavlov, S.
Романенко, Микола Іванович
Александрова, Катерина Вячеславівна
Іванченко, Дмитро Григорович
Левіч, Сергій Вадимович
Павлов, Сергій Васильович
Ключевые слова: acute myocardial infarction
lactate dehydrogenase
protein oxidation
superoxide dismutase
xanthine derivatives
Issue Date: 2017
Издатель: Oxidants and Antioxidants in Medical Science
Библиографическое описание: Study of antioxidant properties of 7-benzyl-8-benzylidene hydrazine xanthine derivatives in vitro and in vivo / L. Yevseyeva, M. Romanenko, K. Aleksandrova [et al.] // Oxidants and Antioxidants in Medical Science. – Режим доступа : https://www.researchgate.net/publication/320367973_Study_of_antioxidant_properties_of_7-benzyl-8-benzylidene_hydrazine_xanthine_derivatives_in_vitro_and_in_vivo.
Аннотация: Objective: Acute myocardial infarction (AMI) plays a leading role in the structure of morbidity and mortality worldwide. One of the main parts of it pathogenesis is production of reactive oxygen species (ROS). The accumulation of ROS in cardiomyocytes results in lipid peroxidation, protein oxidation, DNA damage, and finally cell death. Thereby the search of novel drugs that have antioxidant activity and can be used to complex treatment of myocardial infarction is reasonable. It is known that xanthine derivatives exhibit a broad spectrum of biological activity including antioxidant so that the aim of this research was to study in vitro and in vivo antioxidant action of derivatives of 7-benzyl-8-benzylidene hydrazine xanthines.
URI: http://dspace.zsmu.edu.ua/handle/123456789/11233
Appears in Collections:Наукові праці. (Біохімія)

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