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Please use this identifier to cite or link to this item: http://dspace.zsmu.edu.ua/handle/123456789/13800

Название: Markers of oxidative stress and energy metabolism in the rat myocardium during physical exertion and during the introduc- tion of an antioxidant – 8-benzylaminotheophyllinyl -7-acetic acid hydrazide (C-3)
Авторы: Ryzhenko, V. P.
Bukhtiyarova, N. V.
Levich, S. V.
Ryzhov, O. A.
Makyeyeva, L. V.
Риженко, Віктор Павлович
Бухтіярова, Ніна Вікторівна
Левіч, Сергій Вадимович
Рижов, Олексій Анатолійович
Макєєва, Людмила Валеріївна
Ключевые слова: substance C3
Mildronate
working hypoxia
energy metabolism
oxidative stress
Issue Date: 2019
Издатель: Czech Republic: European Scientific Center Biologial Marker
Библиографическое описание: Markers of oxidative stress and energy metabolism in the rat myocardium during physical exertion and during the introduc- tion of an antioxidant – 8-benzylaminotheophyllinyl -7-acetic acid hydrazide (C-3) [Electronic resource] / V. P. Ryzhenko, N. V. Bukhtiyarova, S. V. Levich, O.A. Ryzhov, L. V. Makyeyeva // Biological Markers in Fundamental and Clinical Medicine. - 2019. - Vol. 3, № 2. - P. 19-26.
Аннотация: One of the tasks of modern pharmacology is the development and creation of remedies that not only increase physical endurance, but also are able to protect target organs (heart, brain, kidneys, etc.) from hypoxia [1,2,3]. A significant increase in physical activity leads to an imbalance between the energy supply of the myocardium and its metabolic needs, i.e. to working hypoxia. During this period, there is an increase in the production of reactive oxygen species (ROS) by the bioenergetic reactions of mitochondria [3,4,5,6]. Oxidative stress develops during insufficient activity of antioxidant systems and an excess of ROS.
URI: http://dspace.zsmu.edu.ua/handle/123456789/13800
ISSN: 2570-5903
Appears in Collections:Наукові праці. (Біохімія)
Наукові праці. (Гістологія, цитологія)
Наукові праці. (Лабораторна діагностика)
Наукові праці. (Медична інформатика)

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