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Please use this identifier to cite or link to this item: http://dspace.zsmu.edu.ua/handle/123456789/15092

Название: Investigation of acute toxicity of novel 3,7-dihydro-1H-purine-2,6-dione derivatives
Авторы: Veretenina, A. A.
Vasylyev, D. A.
Веретеніна, Ася Анатоліївна
Васильєв, Денис Андрійович
Ключевые слова: xanthine
purine
synthesis
acute
toxicity
Issue Date: 2021
Издатель: EEA, INDIA
Библиографическое описание: Veretenina A. A. Investigation of acute toxicity of novel 3,7-dihydro-1H-purine-2,6-dione derivatives / A. A. Veretenina, D. A. Vasylyev // Journal of Life Sciences and Modern Technologies. - EEA, INDIA, 2021. - Vol. 2, №1. – P. 27-31.
Аннотация: The past thirty years of investigation and development in pharmacophore design has produced revolutionary results. Ring structure give molecules their basic form, determine whether molecules are rigid or flexible, and keep substituents in their appropriate sites. In many biologically active structures, rings are directly involved in communications with cell receptors, either through heteroatoms forming hydrogen bonds with suitable protein residues or through hydrophobic interactions. The latter relays to many branches of bioinformatics like in-silico algorithms, biochemical assays, better pharmacokinetics/pharmacodynamics (PK/PD) models, ADME models, and wide variety of toxicology surveys.
URI: http://dspace.zsmu.edu.ua/handle/123456789/15092
Appears in Collections:Наукові праці. (Біохімія)

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