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Please use this identifier to cite or link to this item: http://dspace.zsmu.edu.ua/handle/123456789/5277

Название: Metabolomics in Heart Failure Patients: Hype and Hope
Авторы: Berezin, A. E.
Березін, Олександр Євгенійович
Ключевые слова: Heart failure
Metabolism
Biomarkers
Clinical outcomes
Metabolomics
Proteomics
Issue Date: 2016
Библиографическое описание: Berezin A. E. Metabolomics in Heart Failure Patients: Hype and Hope / A. E. Berezin // J. Biomarkers. – 2016. – Vol. 2, N 3. – P. 21-23.
Аннотация: Heart failure remains a leading cause of death in patients with established cardiovascular disease. The biomarkers reflecting staging and evolution of HF appear to be promised tool to risk stratification and target-based therapy. In the editorial adaptive metabolic transitions of HF with reduced and preserved left ventricular ejection fraction are considered. It has discussed the role of metabolites in the regulating function of the failing heart. The use of metabolites, i.e. polyamines, putrescine, spermidine, spermine, ornithine decarboxylase, and acylcarnitine, in patients with HF is considered. Future directions regarding molecular biology techniques, which substantially contribute to assay of metabolic profile in HF patients aimed improving clinical outcomes, response to the individualized therapy, are emphasized.
URI: http://dspace.zsmu.edu.ua/handle/123456789/5277
Appears in Collections:Наукові праці. (ВХ-2)

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