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Please use this identifier to cite or link to this item: http://dspace.zsmu.edu.ua/handle/123456789/7554

Название: Molecularly-biochemical and neuropsychophysiological aspects of neuroprotective activity of mexidol during chronic immobilizational stress
Авторы: Chekman, I. S.
Yakovleva, I. Yu.
Belenichev, I. F.
Gorchakova, N. A.
Buhtiyarova, N. V.
Бєленічев, Ігор Федорович
Бухтіярова, Ніна Вікторівна
Issue Date: 2013
Издатель: United States : American Society for Pharmacology and Experimental Therapeutics
Библиографическое описание: Molecularly-biochemical and Neuropsychophysiological Aspects of Neuroprotective Activity of Mexidol during Chronic Immobilizational Stress / I. S. Chekman, I. Yu. Yakovleva, I. F. Belenichev, N. A. Gorchakova, N. V. Buhtiyarova // Molecular Pharmacology. – 2013. – Issue 2. – P. 1-6.
Аннотация: Abstract: It is found out that in models of rats’ chronic stress an oral administration of Mexidol (100 mg/kg) during 10 days decreases a degree of DNA oxidative modification markers (8-OHG), proteins APH and KPH, hyperproduction of NO, and activity of NO-synthase. Also it changes an expression of early gene c-Fos and increases a concentration of Bcl-2 in neurons of paraventricular nuclei of the hypothalamus.
URI: http://dspace.zsmu.edu.ua/handle/123456789/7554
ISSN: 0976-3856
Appears in Collections:Наукові праці. (Лабораторна діагностика)
Наукові праці. (Фармакологія та МР)

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