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Please use this identifier to cite or link to this item: http://dspace.zsmu.edu.ua/handle/123456789/8969

Название: Acute toxicity study morpholinium 2-[5-(pyridin-4-yl)-1,2,4- triazol-3-ylthio] acetate in white mice
Авторы: Bushueva, I. V.
Knysh, E. G.
Panasenko, A. I.
Бушуєва, Інна Володимирівна
Панасенко, Олександр Іванович
Книш, Євгеній Григорович
Ключевые слова: morpholinium 2-[5-(pyridin-4-yl)-1,2,4-triazol-3-ylthio] acetate
acute toxicity
parameters of acute toxicity
Issue Date: 2014
Издатель: Канада : Shiny World Corporation
Библиографическое описание: Bushueva I. V. Acute toxicity study morpholinium 2-[5-(pyridin-4-yl)-1,2,4-triazol-3-ylthio] acetate in white mice / I. V. Bushueva, E. G. Knysh, A. I. Panasenko // Intellectual Archive. – 2014. – Vol. 3. – № 4. – P. 20-28.
Аннотация: Creation of new low-emission and high domestic drugs with a wide spectrum of biological activity, which could compete with expensive imported drugs - one of the urgent tasks of pharmaceutical science. A key step in creating original drugs is directed synthesis of biologically active substances with pronounced pharmacological effect and low toxicity. Analysis of scientific literature over the last decade has shown that a great opportunity to create new and effective drug substances have heterocyclic compounds, in particular, derivatives of 1,2,4-triazole. Of particular interest is the morpholinium 2-[5-(pyridin-4-yl)-1,2,4-triazol-3-ylthio] acetate, as a substance with high pharmacological activity. Accordingly, the search for biologically active substances of 1,2,4-triazole, is relevant, has theoretical and practical significance. In the course of the study found that the investigated substance belong to the class of low-toxic or non-toxic compounds.
URI: http://dspace.zsmu.edu.ua/handle/123456789/8969
Appears in Collections:Наукові праці. (Токсикологічна хімія)
Наукові праці. (УЕФ)
Наукові праці. (Клінічна фармація ФПО)

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